Publications

Locotronic

Therapeutic potential of siRNA PMP22-SQ nanoparticles for Charcot-Marie-Tooth 1A neuropathy in rodents and non-human primates
Suzan Boutary, Guy Khalaf, Yosef Landesman, Mevidette el Madani, Didier Desmaële, Françoise Piguet, Rafael Alonso, Elena-Gaia Banchi, David Adams, Charbel Massaad, Liliane Massaad-Massade
https://doi.org/10.1016/j.ijpharm.2025.125234
International Journal of Pharmaceutics
An animal model for Pierpont syndrome: a mouse bearing the Tbl1xr1 Y446C/Y446C mutation
Yalan Hu, Peter Lauffer, Michelle Stewart, Gemma Codner, Steffen Mayerl, Heike Heuer, Lily Ng, Douglas Forrest, Paul van Trotsenburg, Aldo Jongejan, Eric Fliers, Raoul Hennekam, Anita Boelen
doi.org/10.1093/hmg/ddac086
Human Molecular Genetics
Loss of Frrs1l disrupts synaptic AMPA receptor function, and results in neurodevelopmental, motor, cognitive and electrographical abnormalities
Michelle Stewart, Petrina Lau, Gareth Banks, Rasneer Sonia Bains, Enrico Castroflorio, Peter L. Oliver, Christine L. Dixon, Michael C. Kruer, Dimitri M. Kullmann, Abraham Acevedo-Arozena, Sara E. Wells, Silvia Corrochano, Patrick M. Nolan
https://doi.org/10.1242/dmm.039222
Disease Models & Mechanisms
Analysis of motor dysfunction in Down Syndrome reveals motor neuron degeneration
Sheona Watson-Scales, Bernadett Kalmar, Eva Lana-Elola, Dorota Gibbins, Federica La Russa, Frances Wiseman, Matthew Williamson, Rachele Saccon, Amy Slender, Anna Olerinyova, Radma Mahmood, Emma Nye, Heather Cater, Sara Wells, Y. Eugene Yu, David L. H. B
doi : 10.1371/journal.pgen.1007383
PLOS, Genetics
Interferon induces clearance of mutant ataxin 7 and improves locomotion in SCA7 konck-in mice.
Chort A, Alves S, Marinello M, Dufresnois B, Dornbierer JG, Tesson C, Latouche M, Baker DP, Barkats M, El Hachimi KH, Ruberg M, Janer A, Stevanin G, Brice A, Sittler A.
doi: 10.1093/brain/awt061
Brain
Etifoxine improves peripheral nerve regeneration and functional recovery
Christelle Girard, Song Liu, Françoise Cadepond, David Adams, Catherine Lacroix, Marc Verleye, Jean-Marie Gillardin, Etienne-Emile Baulieu, Michael Schumacher, Ghislaine Schweizer-Groyer
doi: 10.1073/pnas.0811201106
Proceedings of the National Academy of Sciences U.S.A.
Use of inducer of promyelocytic leukemia protein (pml) for treating polyglutamine expansion neurodegenerative diseases
Alexandre Janer, Annie Sittler
Demande WO2007147892A2
Demande de brevet
Modulation of behavior and NMDA-R1 gene mRNA expression in adult female mice after sub-acute administration of benzo(a)pyrene
Grova N, Valley A, Turner JD, Morel A, Muller CP, Schroeder H.
http://dx.doi.org/10.1016/j.neuro.2007.01.010
Neurotoxicology
Grafts of Brain-Derived Neurotrophic Factor and Neurotrophin 3-Transduced Primate Schwann Cells Lead to Functional Recovery of the Demyelinated Mouse Spinal Cord
Christelle Girard, Alexis-Pierre Bemelmans, Noëlle Dufour, Jacques Mallet, Corinne Bachelin, Brahim Nait-Oumesmar, Anne Baron-Van Evercooren, and François Lachapelle
http://www.jneurosci.org/cgi/content/abstract/25/35/7924
The Journal of Neuroscience, 25(35):7924-7933
Phospholipid transfer protein (PLTP) deficiency reduces brain vitamin E content and increases anxiety in mice
Catherine Desrumaux, Pierre-Yves Risold, Henri Schroeder, Valérie Deckert, David Masson, Anne Athias, Hélène Laplanche, Naig Le Guern, Denis Blache, Xian-Cheng Jiang, Alan Tall, Didier Desor, and Laurent Lagrost
http://dx.doi.org/10.1096/fj.04-2400fje
The FASEB Journal
Behavioral changes are not directly related to striatal monoamine levels, number of nigral neurons, or dose of parkinsonian toxin MPTP in mice
Estelle Rousselet, Chantal Joubert, Jacques Callebert, Karine Parain, Léon Tremblay, Gaël Orieux, Jean-Marie Launay, Charles Cohen-Salmon and Etienne C. Hirsch
http://dx.doi.org/10.1016/S0969-9961%2803%2900108-6
Neurobiology of Disease, Volume 14, Issue 2, Pages 218-228

Roue d'effort

The effect of Trichinella spiralis on muscular activity of experimentally infected mice
Ionuț Marian, Angela MonicaIonică, Georgiana Deak, Teodor Ursache, Menelaos Lefkaditis, Călin Mircea Gherman, Andrei Daniel Mihalca
https://doi.org/10.1016/j.parint.2019.102032
Parasitology International

Roue d'activité ACTIVYWHEEL avec logiciel

Sex-dependent effects of intestinal epithelial TLR4 deletion induced before activity-based anorexia
Colin Salaün, Marion Huré, Charlène Guérin, Christine Bôle-Feysot, Fatima Léon, Sarah Lenoir, Jean-Luc do-Rego, Jean-Claude do-Rego, Ludovic Langlois, David Ribet, Najate Achamrah, Moïse Coëffier
https://doi.org/10.1101/2025.02.05.636626
Biorxiv
Exercise Prior to Lower Extremity Peripheral Artery Disease Improves Endurance Capacity and Hindlimb Blood Flow by Inhibiting Muscle Inflammation
Maxime Pellegrin, Karima Bouzourène, Lucia Mazzolai
https://doi.org/10.3389/fcvm.2021.706491
Frontiers in Cardiovascular Medicine
The ergogenic impact of the glucocorticoid prednisolone does not translate into increased running motivation in mice
Bastien Redon, Claire Violleau, François Georges, Giovanni Marsicano, Francis Chaouloff
https://doi.org/10.1016/j.psyneuen.2019.104489
Psychoneuroendocrinology
Characterizing the metabolic perturbations induced by activity-based anorexia in the C57Bl/6 mouse using 1 H NMR spectroscopy
Jonathan Breton, Natasa Giallourou, Severine Nobis, Aline Morin, Najate Achamrah, Alexis Goichon, Liliana Belmonte, Pierre Dechelotte, Jean-Luc doRego, Moïse Coëffier, Jonathan Swann
https://doi.org/10.1016/j.clnu.2019.10.026
Clinical Nutrition
The motivation for exercise over palatable food is dictated by cannabinoid type-1 receptors
Carolina Muguruza, Bastien Redon, Giulia R. Fois, Imane Hurel, Amandine Scocard, Claire Nguyen, Christopher Stevens, Edgar Soria-Gomez, Marjorie Varilh, Astrid Cannich, Justine Daniault, Arnau Busquets-Garcia, Teresa Pelliccia, Stéphanie Caillé...
https://dx.doi.org/10.1172%2Fjci.insight.126190
JCI Insight
Changes in Microbiota and Bacterial Protein Caseinolytic Peptidase B During Food Restriction in Mice: Relevance for the Onset and Perpetuation of Anorexia Nervosa
Manon Dominique, Romain Legrand, Marie Galmiche, Saïda Azhar, Camille Deroissart, Charlène Guérin, Jean-Luc do Rego, Fatima Leon, Séverine Nobis, Grégory Lambert, Nicolas Lucas, Pierre Déchelotte
https://doi.org/10.3390/nu11102514
Nutrients
Proteome modifications of gut microbiota in mice with activity-based anorexia and starvation: Role in ATP production
Jonathan Breton P.hD., Romain Legrand P.hD., Najate Achamrah M.D., P.hD., Philippe Chan P.hD., Jean Lucdo Rego P.hD., Jean Claudedo Rego P.hD., Moïse Coëffier P.hD., Pierre Déchelotte M.D., P.hD., Sergueï O.FetissovM.D., P.hD.
https://doi.org/10.1016/j.nut.2019.110557
Nutrition
Glutamine, but not Branched-Chain Amino Acids, Restores Intestinal Barrier Function during Activity-Based Anorexia
Clément L’Huillier, Marine Jarbeau, Najate Achamrah, Liliana Belmonte, Asma Amamou, Séverine Nobis, Alexis Goichon, Emmeline Salameh, Wafa Bahlouli, Jean-Luc do Rego, Pierre Déchelotte, Moïse Coëffier
https://doi.org/10.3390/nu11061348
Nutrients
Beyond the Activity-Based Anorexia Model: Reinforcing Values of Exercise and Feeding Examined in Stressed Adolescent Male and Female Mice
Imane Hurel, Bastien Redon, Amandine Scocard, Meryl Malezieux, Giovanni Marsicano, Francis Chaouloff
https://doi.org/10.3389/fphar.2019.00587
Front. Pharmacol.
Effects of 6 weeks of betaine or C-phycocyanin supplementation associated or not with wheel running on redox status
C. Dupuis, J.Y.Berthon, J.Larue, S.Rougé, M.Filaire, E.Filaire
doi : 10.1016/j.scispo.2017.08.006
Science & Sports
Colonic Mucosal Proteome Signature Reveals Reduced Energy Metabolism and Protein Synthesis but Activated Autophagy during Anorexia‐Induced Malnutrition in Mice
Séverine Nobis, Najate Achamrah, Alexis Goichon, Clément L'Huillier, Aline Morin, Charlène Guérin, Philippe Chan, Jean Luc do Rego, Jean Claude do Rego, David Vaudry, Pierre Déchelotte, Liliana Belmonte, Moïse Coëffier
https://doi.org/10.1002/pmic.201700395
Proteomics
Delayed gastric emptying and altered antrum protein metabolism during activity-based anorexia
S. Nobis, A. Morin, N. Achamrah, L. Belmonte, R. Legrand, P. Chan, J.-L. do Rego, D. Vaudry, G. Gourcerol, P. Déchelotte, A. Goichon, M. Coëffier
dx.doi.org/10.1111
Neurogastroenterology & Motility
Alterations of proteome, mitochondrial dynamic and autophagy in the hypothalamus during activity-based anorexia
Séverine Nobis, Alexis Goichon, Najate Achamrah, Charlène Guérin, Saida Azhar, Philippe Chan, Aline Morin, Christine Bôle-Feysot, Jean Claude do Rego, David Vaudry, Pierre Déchelotte, Liliana Belmonte & Moïse Coëffier
doi: 10.1038/s41598-018-25548-9
Scientific Reports
Sex differences in response to activity-based anorexia model in C57Bl/6 mice
Najate Achamrah, Séverine Nobis, Alexis Goichon, Jonathan Breton, Romain Legrand, Jean Luc do Rego, Jean Claudedo Rego, Pierre Déchelotte, Sergueï O Fetissov, Liliana Belmonte, Moïse Coëffier
doi : 10.1016/j.physbeh.2016.12.014
Physiology & Behavior
Maintaining a regular physical activity aggravates intramuscular tumor growth in an orthotopic liposarcoma model
Mohamad Assi, Frédéric Derbré, Luz Lefeuvre-Orfila, Dany Saligaut, Nathalie Stock, Mickael Ropars, and Amélie Rébillard
PMCID: PMC5446473
American Journal of Cancer Research
Urolithin A induces mitophagy and prolongs lifespan in C. elegans and increases muscle function in rodents
Dongryeol Ryu, Laurent Mouchiroud, Pénélope A Andreux, Elena Katsyuba, Norman Moullan, Amandine A Nicolet-dit-Félix, Evan G Williams, Pooja Jha, Giuseppe Lo Sasso, Damien Huzard, Patrick Aebischer, Carmen Sandi, Chris Rinsch & Johan Auwerx
doi:10.1038/nm.4132
Nature Medicine (2016)
Maintaining physical activity during refeeding improves body composition, intestinal hyperpermeability and behavior in anorectic mice
Najate Achamrah, Séverine Nobis, Jonathan Breton, Pierre Jésus, Liliana Belmonte, Brigitte Maurer, Romain Legrand, Christine Bôle-Feysot, Jean Luc do Rego, Alexis Goichon, Jean Claude do Rego, Pierre Déchelotte, Sergueï O Fetissov, Sophie Claeyssens & Moï
doi:10.1038/srep21887
Scientific Reports 6, Article number: 21887
Skeletal Muscle Expression of the Adhesion-GPCR CD97: CD97 Deletion Induces an Abnormal Structure of the Sarcoplasmatic Reticulum but Does Not Impair Skeletal Muscle Function
Tatiana Zyryanova, Rick Schneider, Volker Adams, Doreen Sittig, Christiane Kerner, Claudia Gebhardt, Henrik Ruffert, Stefan Glasmacher, Pierre Hepp, Karla Punkt, Jochen Neuhaus, Jörg Hamann, Gabriela Aust
PLOS ONE 10.1371/journal.pone.0100513
PLOS ONE, Research Article
Physical activity: benefit or weakness in metabolic adaptations in a mouse model of chronic food restriction?
Mathieu Méquinion, Emilie Caron, Sarah Zgheib, Alicia Stievenard, Philippe Zizzari, Virginie Tolle, Bernard Cortet, Stéphanie Lucas, Vincent Prevot, Christophe Chauveau, Odile Viltart
10.1152/ajpendo.00340.2014
American Journal of Physiology - Endocrinology and Metabolism
Emotional consequences of wheel running in mice: which is the appropriate control?
Dubreucq S, Marsicano G, Chaouloff F
Hippocampus
Hippocampus
CB1 receptor deficiency decreases wheel-running activity: Consequences on emotional behaviours and hippocampal neurogenesis
Sarah Dubreucq, Muriel Koehl, Djoher N. Abrous, Giovanni Marsicano, Francis Chaouloff
Experimental Neurology
Experimental Neurology

Roue d'activité avec identification

Longitudinal [18]UCB-H/[18F]FDG imaging depicts complex patterns of structural and functional neuroplasticity following bilateral vestibular loss in the rat
Melissa Antons, Magdalena Lindner, Maximilian Grosch, Rosel Oos, Giovanna Palumbo, Matthias Brendel, Sibylle Ziegler, Peter Bartenstein, Marianne Dieterich & Andreas Zwergal
www.nature.com/articles/s41598-022-09936-w#citeas
Scientific Reports

Cage & mini roue d'activité avec compteur

Skeletal muscle ceramides do not contribute to physical-inactivity-induced insulin resistance
Zéphyra Appriou, Kévin Nay, Nicolas Pierre, Dany Saligaut, Luz Lefeuvre-Orfila, Brice Martin, Thibault Cavey, Martine Ropert, Olivier Loréal, Françoise Rannou-Bekono, Frédéric Derbré
https://doi.org/10.1139/apnm-2018-0850
Physiologie appliquée, nutrition et métabolisme

Puce TAM-S (1,25 x 7 mm)

Use of Rgg quorum-sensing machinery to create an innovative recombinant protein expression system in Streptococcus thermophilus
Rozenn Gardan, Edith Honvo-Houeto​, Christine Mézange​, Nathanael Jean Maillot, Aurélie Balvay, Sylvie Rabot, Luis G. Bermúdez-Humarán, Philippe Langella, Véronique Monnet
https://doi.org/10.1099/mic.0.001487
Microbiology
Evaluation of a European sea bass (Dicentrarchus labrax L.) post-larval tagging method with ultra-small RFID tags
Sara Faggion, Pierre Sanchez, Marc Vandeputte, Frédéric Clota, Alain Vergnet, Marie-Odile Blanc, François Allal
https://doi.org/10.1016/j.aquaculture.2020.734945
Aquaculture

Mangeoire amovible avec pesée

Ultradian feeding in mice not only affects the peripheral clock in the liver, but also the master clock in the brain.
Sen S, Raingard H, Dumont S, Kalsbeek A, Vuillez P, Challet E
DOI: 10.1080/07420528.2016.1231689
Chronobiology International
Rev-erbα in the brain is essential for circadian food entrainment
Julien Delezie, Stéphanie Dumont, Cristina Sandu, Sophie Reibel, Paul Pevet & Etienne Challet
doi:10.1038/srep29386
Scientific Reports 6, Article number: 29386